Renal protection in sepsis: Is hypertonic sodium (lactate) the solution?
نویسندگان
چکیده
منابع مشابه
Sepsis volume reposition with hypertonic saline solution.
The present review discusses the hemodynamic and immune-modulatory effects of hypertonic saline in experimental shock and in patients with sepsis. We comment on the mechanisms of action of hypertonic saline, calling upon data in hemorrhagic and septic shock. Specific actions of hypertonic saline applicable to severe sepsis and septic shock are highlighted. Data available support potential benef...
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Hypertonic saline solution can absorb part of the intracellular fluid volume into the extracellular space. The effects of this solution on the cardiovascular system are increased coronary flow and increased left ventricular contraction, without sympathetic system activation. This study was designed to assess the effects of hypertonic saline solution in open heart surgery and to compare it w...
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The review by Oliveira and colleagues on the subject of hypertonic saline resuscitation in sepsis (included in the present issue) suggests possible benefits for hypertonic saline. There is a firm experimental basis for the actions of hypertonic saline/hyperoncotic solutions in hemorrhagic hypotension, which include expansion of blood volume, improvement in cardiac index, favorable modulation of...
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The resuscitation of patients in sepsis is a challenge for many reasons. One of the important questions is: Who needs what kind of resuscitation? In the present guidelines, resuscitation is mostly directed at patients with a high risk of mortality. In this review, I will discuss the value of using lactate levels to identify patients who might benefit from treatment and how to use sequential lac...
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ژورنال
عنوان ژورنال: Annals of Intensive Care
سال: 2019
ISSN: 2110-5820
DOI: 10.1186/s13613-019-0505-z